Why This Summit Is Unmissable for Scientists
Discover New Approaches to RNA Target Selection, Screening & Drug Design.
This summit is built around the technical challenges preventing RNA-targeted therapeutics from reaching their full potential.
Learn how leading teams are solving challenges in target identification, screening, structural analysis, selectivity assessment, translational validation, and mechanism characterization. Return with practical ideas that can directly influence your research strategy.
Challenges We Help Solve
Distinguishing Functional Targets from Druggable Targets
Learn how teams are identifying RNA structures that not only bind molecules but also drive meaningful biological outcomes.
Improving Screening Success
Benchmark affinity-based, fragment-based, phenotypic, and cell-based screening approaches to identify strategies that generate more actionable hits.
Characterizing RNA-Small Molecule Interactions
Discover new structural biology, cryo-EM, computational, and biophysical approaches to better understand RNA binding and mechanism of action.
Measuring Selectivity & Target Engagement
Gain practical insight into how leading organizations are assessing on-target activity, functional modulation, and translational relevance.
Translating Discovery Into Development
Understand what datasets, validation methods, and experimental evidence are required to advance promising RNA-targeted candidates.
Priority Sessions for Scientists
Advancing RNA Structure Probing & Target Engagement Analysis
Workshop B: Moving Beyond Secondary Structures: Advancing RNA Structure Probing Technologies to Measure Small Molecule-RNA Interactions & Guide Optimization
Speakers:
- Kevin Weeks, Distinguished Professor of Chemistry, UNC Chapel Hill
- Matt Smola, Director of RNA Platform Development, Ribometrix
Understand cutting-edge technologies for measuring RNA structure, characterizing binding interactions, and improving confidence in target engagement decisions.
Improving Target Selection Through AI & Structural Biology
Conference Day One: Prioritizing Ligandable RNA Targets with AI-Enabled Structure Prediction & Functional Validation
Speakers:
- Raphael Townshend, Chief Executive Officer, Atomic AI
Learn how AI-driven structure prediction and experimental validation are helping teams identify therapeutically relevant RNA targets before committing resources to screening campaigns.
Measuring Selectivity Across RNA-Targeted Approaches
Conference Day Two: Roundtable Discussion: Measuring Selectivity Across RNA-Targeted Small Molecule Approaches to Build Functional Confidence
Moderator:
- Amanda Hargrove, Director & Professor - Medicinal Chemistry, University of Toronto
Benchmark strategies for evaluating selectivity, understanding on-target activity, and generating the functional evidence required to support development decisions.
Benchmark Your Strategy Against Peers
Questions you could ask your peers to benchmark against them:
How are organizations validating RNA target engagement?
Which screening technologies are producing the highest-quality hits?
What role is AI playing in RNA target selection and hit optimization?
How are teams defining acceptable selectivity profiles?
Which translational models are generating the most predictive datasets?
What Past Attendees Say
What stood out to me was the strong balance between fundamental RNA biology, emerging technologies, and translational perspectives across pharma and biotech. The highly engaged audience and the frank exchange of technical challenges made the sessions particularly valuable.
The RNA-targeted drug discovery summit is a premier event that brings together a wide range of scientists involved in RNA drug discovery. It's a great opportunity to catch up on the latest developments in the field and compare notes with peers. I highly recommend this event to all practitioners in the area.