Why This Summit Is Unmissable for Scientists

Discover New Approaches to RNA Target Selection, Screening & Drug Design.

This summit is built around the technical challenges preventing RNA-targeted therapeutics from reaching their full potential.

Learn how leading teams are solving challenges in target identification, screening, structural analysis, selectivity assessment, translational validation, and mechanism characterization. Return with practical ideas that can directly influence your research strategy.

Scientist Networking

Challenges We Help Solve

Challenges Solved RNA DDD Number 1

Distinguishing Functional Targets from Druggable Targets

Learn how teams are identifying RNA structures that not only bind molecules but also drive meaningful biological outcomes.

Challenges Solved RNA DDD Number 2

Improving Screening Success

Benchmark affinity-based, fragment-based, phenotypic, and cell-based screening approaches to identify strategies that generate more actionable hits.

Challenges Solved RNA DDD Number 3

Characterizing RNA-Small Molecule Interactions

Discover new structural biology, cryo-EM, computational, and biophysical approaches to better understand RNA binding and mechanism of action.

Challenges Solved RNA DDD Number 4

Measuring Selectivity & Target Engagement

Gain practical insight into how leading organizations are assessing on-target activity, functional modulation, and translational relevance.

Challenges Solved RNA DDD Number 5

Translating Discovery Into Development

Understand what datasets, validation methods, and experimental evidence are required to advance promising RNA-targeted candidates.

Priority Sessions for Scientists

Advancing RNA Structure Probing & Target Engagement Analysis

Workshop B: Moving Beyond Secondary Structures: Advancing RNA Structure Probing Technologies to Measure Small Molecule-RNA Interactions & Guide Optimization

Pre-Conference Day

Speakers:

  • Kevin Weeks, Distinguished Professor of Chemistry, UNC Chapel Hill
  • Matt Smola, Director of RNA Platform Development, Ribometrix

Understand cutting-edge technologies for measuring RNA structure, characterizing binding interactions, and improving confidence in target engagement decisions.

Kevin Weeks UNC Chapel Hill professor RNA structure chemistry expert
Matt Smola Ribometrix RNA biology expert small molecule targeting RNA
UNC Chapel Hill
Ribometrix
Improving Target Selection Through AI & Structural Biology

Prioritizing Ligandable RNA Targets with AI-Enabled Structure Prediction & Functional Validation

Conference Day One

Speaker:

  • Raphael Townshend, Chief Executive Officer, Atomic AI

Learn how AI-driven structure prediction and experimental validation are helping teams identify therapeutically relevant RNA targets before committing resources to screening campaigns.

Raphael Townshend Atomic AI CEO AI drug discovery biotech leader
Atomic AI
Measuring Selectivity Across RNA-Targeted Approaches

Roundtable Discussion: Measuring Selectivity Across RNA-Targeted Small Molecule Approaches to Build Functional Confidence

Conference Day Two

Moderator:

  • Amanda Hargrove, Director & Professor - Medicinal Chemistry, University of Toronto

Benchmark strategies for evaluating selectivity, understanding on-target activity, and generating the functional evidence required to support development decisions.

Amanda Hargrove University Toronto medicinal chemistry RNA targeting expert
University of Toronto logo

Benchmark Your Strategy Against Peers

Questions you could ask your peers to benchmark against them:

How are organizations validating RNA target engagement?

Which screening technologies are producing the highest-quality hits?

What role is AI playing in RNA target selection and hit optimization?

How are teams defining acceptable selectivity profiles?

Which translational models are generating the most predictive datasets?

What Past Attendees Say

xForestTherapeutics logo

What stood out to me was the strong balance between fundamental RNA biology, emerging technologies, and translational perspectives across pharma and biotech. The highly engaged audience and the frank exchange of technical challenges made the sessions particularly valuable.

ReviR Therapeutics logo

The RNA-targeted drug discovery summit is a premier event that brings together a wide range of scientists involved in RNA drug discovery. It's a great opportunity to catch up on the latest developments in the field and compare notes with peers. I highly recommend this event to all practitioners in the area.

Turn RNA Innovation Into Action

From identifying functional RNA targets and optimizing lead compounds to securing strategic partnerships and evaluating new modalities, this summit is designed to help you overcome the challenges facing the next generation of RNA-targeted therapeutics.

Explore the latest scientific advances, connect with peers facing similar challenges, and leave with practical insights you can immediately apply to your research, pipeline, and business strategy.

Secure your place today or explore the full agenda to discover the sessions most relevant to you.