Using Scalable RNA Screening to Accelerate RNA-Targeted Drug Discovery
- Moving beyond case-by-case RNA discovery by developing scalable screening workflows that identify functional RNA structures and tractable targets earlier
- Comparing fragment-based, affinity-based, and cell-based screening approaches to determine which technologies generate actionable RNA-targeted hits
- Prioritizing functional output over binding alone to reduce false positives and identify compounds with meaningful RNA-modulating activity