Small Molecules Modulate Stability of MALAT1 Substructures
Time: 1:15 pm
day: Conference Day Two
Details:
• RNA-targeted libraries yield small molecule modulators of RNA conformation and function
• Oncogenic MALAT1 lncRNA contains ligandable substructures with putative function
• Tunable small molecules modulate MALAT1: protein interactions and lead to rapid degradation
