Matt Woll
Company: PTC Therapeutics
Job title: Senior Vice President of Chemistry
Seminars:
PTC Splice Modulators: From a Novel Discovery to a Broad Therapeutic Platform (PTSeek) 9:00 am
Sequence specific splice modulators have demonstrated therapeutic application for SMA and HD PTC has designed a discovery platform, PTSeek, that couples proprietary splicing data analysis tools with a unique library of small molecules Several novel series of molecules are being advanced to influence the expression of disease relevant genes through splicing modulation Novel splicing modulators…Read more
day: Conference Day One
Panel Discussion Increasing Chemical Diversity in RNA-Targeted Splice Modulator Small Molecules to Expand the Target Space & Address Previously Undruggable Diseases 1:00 pm
• How can expanding the target space beyond the common splice modulators unlock new opportunities for targeting novel disease areas • What strategies are enabling the design of chemically diverse scaffolds to overcome current limitations in the ligand design space • Are we overdependent on nonsense-mediated decay and can reducing this reliance drive broaden therapeutic…Read more
day: Conference Day One