Chris Burge

Company: Massachusetts Institute of Technology

Job title: Whitaker Professor of Biology

Seminars:

Splicing: Predictive Models & Variability Between People 11:00 am

KATMAP learns a regulatory activity map for splicing factors using knockdown and in vitro RNA-binding data Direct regulatory target exons and associated regulatory elements are predicted Using GTEx RNA-seq data, we have identified tens of thousands of “naturally variable exons” (NVEs) that are spliced in some people but not others and shown that NVEs aid…Read more

day: Day Two

Uncovering RNA Targets Beyond Splicing Modifiers to Expand the Potential of RNA Targeting for Treating More Diseases 3:10 pm

There are many novel RNA targets in addition to splice sites, such as long non-coding RNAs which have highly structured motifs, meaning they are good targets. Hence, understanding the new and innovative areas to expand this field is exciting and can increase the potential of treating more diseases. This session will focus on: Uncovering the…Read more

day: Workshop Day