Amanda Hargrove

Company: Duke University

Job title: Professor of Chemistry

Seminars:

Panel Discussion: Overcoming Key Challenges to Improve Drug Design & Discovery for Novel Approaches 3:30 pm

Navigating the current landscape of small molecules targeting RNA How can the unlimited potential to target RNA with small molecules be explored and exploited to develop novel approaches? What are the lessons from other modalities that can be leveraged to develop small molecules that target RNA? What needs to happen for this modality to become…Read more

day: Day 1 PM

Evaluating How to Choose the Best Small Molecules to Achieve Desired On-Target Effects 12:15 pm

With the increasing research in small molecule-RNA targeting over the last decade and advances in machine learning, there is a growing consensus around the distinct and predictive properties that distinguish RNA-targeting small molecules from those that target proteins. It is also clear that RNAtargeting small molecules can look very similar to typical small molecule drugs.…Read more

day: Pre-Conference Workshop Day