Joshua Apgar

Joshua Apgar

Company: Applied BioMath

Job title: Co-founder and Chief Scientific Officer


Mechanistic Modeling to support Translation of mRNA Therapies from Discovery to Clinic 12:20 pm

Crigler-Najjar syndrome type 1 (CN1) is an autosomal recessive disease caused by a marked decrease in uridine-diphosphate-glucuronosyltransferase (UGT1A1) enzyme activity with limited treatment options In this talk, we will discuss the application of quantitative systems pharmacology (QSP) modeling to the design and development of an LNP-delivered mRNA gene therapy for the treatment of CN1 We…Read more

day: Day 1 Track B AM

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