John Schneekloth

Company: National Cancer Institute

Job title: Senior Principal Investigator

Seminars:

Structure- & Fragment- Based Design of Small Molecule RNA Imaging Agents 4:00 pm

Fluorogenic RNA aptamers are powerful tools to image RNA in live cells Broad adaptation of this technology requires new, brighter fluorophore systems Structure- and fragment- based design enables the discovery of an ultrabright RNA activated fluorophoreRead more

day: Day Two

Investigating RNA Off-Target Effects of FDA Approved Drugs to Understand Pharmacology 12:30 pm

Small molecule screening reveals many drug-like compounds bind to RNA Using AI/ML to understand that many FDA approved drugs have RNA binding potential Transcriptome-wide binding and functional analysis reveals the impact of RNA binding on off-target pharmacologyRead more

day: Focus Day