Domi Stickens

Company: Arrakis Therapeutics

Job title: Vice President, Discovery Biology & Translational Sciences

Seminars:

Panel Discussion: Evaluating High-Value Direct RNA & Protein/RNA Complex Target Traits for Ensuring Efficient Binding & Therapeutic Effect for Accelerating Relevant Drug Discovery 12:10 pm

What are the key characteristics which validated RNA and RNA/protein targets share? How to conduct high resolution characterization of RNA targets including the different proteins and binding compounds present in the body How to determine RNA sub-targets which can be both bound by small molecule targets and cause therapeutic effectsRead more

day: Day One

Genetic Medicines: Discovering Small Molecules that Interdict RNA Function 2:00 pm

RNA targets are now broadly validated clinically and commercially, but many attractive targets remain out of reach to current modalities Arrakis has built a novel and highly differentiated platform for discovering drug-like small molecule ligands for RNA targets Arrakis platform has thus far produced at least two small molecule programs that clearly mimic the biological…Read more

day: Day One