Unlocking the Therapeutic Potential of Small Molecule mRNA Splicing Modulators to Prevent Somatic Expansion in Huntington’s Disease
Time: 12:30 pm
day: Day Two
Details:
- Exploring the molecular mechanisms by which small molecule mRNA splicing modulators interact with the mismatch repair (MMR) pathway to prevent somatic expansion
- Summarizing results from in vivo studies that evaluate the therapeutic potential of small molecule mRNA splicing modulators to address somatic expansion
- Highlighting key findings that show the impact on the mismatch repair pathway, including changes in gene expression, protein levels, and cellular phenotypes relevant to Huntington's Disease
