Uncovering RNA Targets Beyond Splicing Modifiers to Expand the Potential of RNA Targeting for Treating More Diseases
Time: 3:10 pm
day: Workshop Day
Details:
There are many novel RNA targets in addition to splice sites, such as long non-coding RNAs which have highly structured motifs, meaning they are good targets. Hence, understanding the new and innovative areas to expand this field is exciting and can increase the potential of treating more diseases.
This session will focus on:
- Uncovering the involvement of long non-coding RNAs in disease and understanding if they are suitable to target by small molecules
- Identifying new disease relevant RNA sequences, beyond splice sites
- Highlighting RNA targets for ASOs which may be relevant for targeting by small molecule drugs for better oral bioavailability
- How can targeting repeat RNAs lead to functional consequences?
