Advancing RNA-Targeted Drug Discovery Through Biophysical & Kinetic Characterization of Small Molecule/RNA Interactions

• Applying single-molecule and kinetic methods to characterize RNA–small moleculeminteractions in depth
• Defining the precise molecular species bound by RNA-targeting drugs to strengthen assay design and screening strategies
• Translating mechanistic insights into more informed hit identification, target engagement studies, and therapeutic development decisions

Speakers:

Aaron Hoskjns

Wasson Professor in Biochemistry

University of Wisconsin-Madison