Jimin Hwang
Company: Pyle Lab at Yale University
Job title: Researcher
Bio:
Education: Chemical Engineering (BS, Hanyang University), Chemical and Biological Engineering (MEng, Korea University), Chemistry and Chemical Biology (PhD, Max Planck Institute of Molecular Physiology)
Research: Small molecule drug discovery for antifungal agent by targeting RNA (Group I self-splicing intron)
Favorite molecule: β-D-Fructofuranosyl α-D-glucopyranosid
Favorite place in New Haven: The Whale Tea
Outside of lab, I enjoy: Hiking, watching sports games
Seminars:
Targeting Group I Introns with Small Molecules: Unlocking a New Antifungal Mechanism Through RNA Targeting 3:45 pm
• Identifying self-splicing Group I introns as a novel RNA target in human-pathogenic fungi, such as Candida albicans, highlighting a unique RNA-targeting mechanism distinct from existing antifungal drugs • Developing small molecule inhibitors through FRET-based high-throughput screening, followed by structure activity relationship (SAR) analysis and mechanistic insights guided by cryo-EM structural data • Demonstrating potent…Read more
day: Conference Day Two