David Sparkman-Yager
Seminars
Wednesday 11th November 2026
Optimization & Functional Characterization of MYC RNA-Targeting Small Molecules
4:00 pm
- Elucidating compound mechanism by defining how mRNA-targeted MYC repression drives modulation of the MYC transcriptional network
- Demonstrating in vivo efficacy to show translation from cellular activity into disease-relevant models
- Enhancing efficacy by refining potency, exposure, and selectivity
