David Sparkman-Yager
Company: Wayfinder Biosciences
Job title: Chief Technology Officer
Bio:
David Sparkman‑Yager, PhD is Co‑Founder & Chief Technology Officer at Wayfinder Biosciences, where he co-designed an AI‑driven platform to develop RNA‑targeting small molecules and biosensors for undruggable transcripts. Based in Seattle, he holds a PhD in molecular engineering from the University of Washington and is recognized for pioneering programmable RNA‑ligand interaction design that accelerates RNA therapeutic discovery .
Seminars:
Conformation-Driven Biochemical Screening Approach Discovers Functional RNA Binders that Modulate Myc Translation In Cancer 11:45 am
• Discovering selective binders for translational regulatory elements in the Myc mRNA using Wayfinder’s highly quantitative HTS platform • Validating functional activity and drug-like properties while reaching sub-micromolar potency via compound optimization • Elucidating compound targeting profile and tumor-specific mechanism of actionRead more
day: Conference Day Two