Balajee Somalinga
Seminars
Thursday 4th December 2025
Targeting HTT RNA & Translation for Allele-Selective Lowering of Mutant Huntingtin
2:15 pm
• Validating HTT exon1 as a target for allele-selective targeting in HD
• Identifying and profiling of allele-preferential HTT RNA binding small molecules
• Exploring opportunities for targeting uORF regulatory mechanisms in HTT translation
