Breaking the Dimensional Limits of RNA–Ligand Discovery: High- Throughput Insights into Structure, Selectivity, & Function

Time: 2:00 pm
day: Conference Day One

Details:

• Characterizing RNA motifs with both ligandable pockets & functional elements to improve druggability & achieve mechanism-based targeting

• High-resolution quantification of RNA–ligand binding enables SAR-guided optimization from submicromolar hits to nanomolar binders

• Interaction big data-driven delineation of novel chemical space to inform future design of selective drug-like RNA binders

Speakers: