Breaking the Dimensional Limits of RNA–Ligand Discovery: High- Throughput Insights into Structure, Selectivity, & Function
Time: 2:00 pm
day: Conference Day One
Details:
• Characterizing RNA motifs with both ligandable pockets & functional elements to improve druggability & achieve mechanism-based targeting
• High-resolution quantification of RNA–ligand binding enables SAR-guided optimization from submicromolar hits to nanomolar binders
• Interaction big data-driven delineation of novel chemical space to inform future design of selective drug-like RNA binders
Speakers:
