Rational Design of Small Molecule Modulators of RNA: Opportunities & Challenges
Time: 9:00 am
day: Pre-Conference Focus Day
Details:
- Targeting RNA with small molecules provides an opportunity to modulate “undruggable” protein targets indirectly
- The integration of structural, biophysical, and computational methods has proven to be successful in the rational design of small molecules directed to protein targets
- The relative immaturity of these methods applied to RNA creates a challenge for the rational design of small molecules directed to RNA targets
