Rational Design of Bioactive Small Molecules Targeting RNA

Time: 9:00 am
day: Day One


• Exploring the utility of different compounds as both advancers of lead medicines and as chemical probes to advance understanding of previously unknown RNA biology
• Highlighting how the sequence-based small molecule rational design tool, dubbed Inforna, allows for targeted degradation of RNAs in cells and animals
• Understanding how these advances imply a necessary reassessment for
the future for SMIRNAs to deliver precision medicines