Small Molecules Modulate Stability of MALAT1 Substructures
Time: 3:30 pm
day: Day Two
Details:
- RNA-targeted libraries yield small molecule modulators of RNA conformation and function
- Oncogenic MALAT1 lncRNA contains ligandable substructures with putative function
- Tunable small molecules modulate MALAT1: protein interactions and lead to rapid degradation
