Finding & Characterizing Small-Molecule Compounds Binding to Non-Coding RNA Targets Using Affinity-Selection MS

Time: 2:30 pm
day: Day Two


  • Affinity-selection MS screening can find binders to a wide variety of RNA targets
  • RNA-binding ligands can then be profiled to determine structural features that bias them to bind to RNA targets
  • Biophysical and cell-based techniques have been applied to characterize activities of novel binders to be bacterial and mammalian non-coding RNA targets